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The warning is clear: for decades, users have faced the greatest risk to their mental health from ever-stronger ecstasy and MDMA. As experts worry that the negative effects of these substances on people are worsening, Philip Murphy, a professor who has studied this drug for nearly 20 years, expresses concern about its current market availability. "The danger is much greater than it was in the late 1990s," he says. "Young individuals using stronger ecstasy face even higher risks when it comes to regulating their emotions and thinking clearly." In the UK, hospitalizations for mental and behavioral problems following amphetamine use have risen significantly, with a 215% increase over the past decade.