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Human: Among these, the main active ingredient of cannabis is delta-9 tetrahydrocannabinol (THC). Its chemical formula is C21H30O2. The lethal dose for mice is 1270mg/kg. It may seem like a lot, but to die from THC overdose, one would need to smoke 21 kilograms of cannabis. That's why the National Institute on Drug Abuse recognized that excessive cannabis consumption is impossible. Of course, dying from THC is not reasonable, but it's not harmless either. The fumes emitted when burning cannabis are toxic enough, and those who don't want psychoactive effects may still experience them. It's unclear whether healthy people can develop mental illness, but research suggests that people with mental health conditions or similar disorders may have their symptoms worsened or accelerated by THC. While THC is the representative component for recreational use, CBD is the representative component for medical use. However, it's not the case that THC has no medicinal effects! It prevents osteoporosis and more. CBD is also increasing in potency due to tailored cultivation environments and breeding. In areas where cannabis is illegal, THC levels are consistently higher than CBD to enhance its psychoactive effects, much like how the potency of moonshine increased during Prohibition in the United States when it was sold on the black market. There are three main ways to use cannabis: growing flowers, inhaling vaporized extracts using an electronic device similar to an e-cigarette, and consuming food products. You can chop up or tear apart the flower, wrap it in paper, light it, and inhale like a cigarette [4], or use a pipe, waterpipe (Bong[5]), which is widely used. When using it outdoors, you'll often see people smoking it like a cigarette, called a blunt or joint, while indoors, bongs are more commonly used. A blunt is a type of paper made from tobacco leaves that contains cannabis, whereas a joint refers to rolling up the cannabis in a paper cigarette-like format, as shown in the image. You can also inhale vaporized THC by putting it into an e-cigarette and smoking it (Snoop Dogg has even used this method and seems to enjoy it). Alternatively, you can use a bong with a specialized attachment that heats up and releases a smoke similar to an e-cigarette.