
Vancomycin-final-24/3/16
thingiverse
This is part of an antibiotic called vancomycin. Antibiotics are molecules that block bacterial and fungal metabolism by binding to specific structures. Vancomycin is one of these molecules, used to control gram-positive bacteria growth. It tightly binds to D-alanine-D-alanine peptide, a crucial structure for crosslink formation between peptides. This model was created with Tinkercad. Edit it online at https://www.tinkercad.com/things/6urz5Do8AwT Print Settings: Printer Brand: MakerBot Printer: MakerBot Replicator (5th Generation) Rafts: Yes Supports: No Notes: When printing this model, I downloaded the pdb file from RCSB. Then, I imported it into VMD software for modifications and selections. Next, I adjusted sphere resolution to 15 and size to 2.5, then scaled up its size to 4.0 to ensure printability. After rendering in STL form, I converted it to Tinkercad. To prepare for printing, select and modify the molecule's angle in Tinkercad and download as an STL file. Then, check the model's size using MakerBot. If suitable, add supports to the model while paying attention to stick height. Some sticks may be too tall to hold the ball, causing it to fall. To resolve this issue, add rafts to strengthen these sticks. Once completed, convert the model back to Makerbot and wait for 3-4 hours for printing to finish.
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