
Mutant GATA-1 and FOG
sketchfab
Human cells exhibit mutations in the N-finger region of the GATA-1 protein, specifically V205M (Pink), G208S (Purple), D218G (Yellow) and R216Q (Green). The DNA interacts closely with the DNA-binding surface of GATA-1, colored grey. Meanwhile, Friend of GATA-1 (FOG) binds to GATA-1 at its FOG-interacting face, represented in light blue.
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