Karyotype Laboratory Exercise

Karyotype Laboratory Exercise

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Here is the rewritten text: Genetics students use this model to learn about karyotypes by simulating actual genetic testing. The goal is to perform a karyotype by identifying every chromosome. Students receive a full set and descriptions of each chromosome, then pair the chromosomes with their homologs. They can also identify chromosomal sex, translations, deletions, or transmutations. This lesson was developed for the NCSU Genetics department through a Diversity Mini-Grant from North Carolina State University. Print Settings Printer Brand: LulzBot Printer: Mini Infill: 15 and up Notes: The Karyotype Model file prints one half of the karyotype. Two prints will take about 4-5 hours at lower resolution. High resolution is not necessary. Two prints of the main karyotype file create an XXYY model. The other model file, indicated in yellow on the photo, shows Burkitt's Lymphoma, Chronic Myelogenous Leukemia, and Down Syndrome (Trisomy 21). Designing This Chromosomes were normalized to 100mm using data on base pairs. Centromeres were calculated using this data. This scale fits on the print bed of the Lulzbot mini. In Autodesk Fusion 360, a curve was made from chromosome photos and descriptions. Chromosomes were flattened for better print bed adhesion. The flat face was extended 1mm to increase rigidity. References This file was created through a Diversity Mini-Grant from North Carolina State University.

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