Insulin Hexamer

Insulin Hexamer

thingiverse

The three models are of an insulin hexamer. Three molecules of insulin are coordinated by a zinc ion to form a trimer. Two of these trimers are interlocked to form the hexamer. https://en.wikipedia.org/wiki/Insulin The structure was taken from the protein database: https://www.rcsb.org/structure/1aiy In this particular case, the data of the three-dimensional solution structure of the phenol-stabilized 36 kDa R6 insulin hexamer was determined by NMR spectroscopy and restrained molecular dynamics. The paper can be found here: X. Chang, A. M. Jørgensen, P. Bardrum, J. J. Led, Biochemistry-Us 1997, 36, 9409–9422. https://pubs.acs.org/doi/10.1021/bi9631069 Water and phenol molecules where deleted from the structural data and STLs were made with VDM. The file endings 07, 08, and 10 denote the factor that was used on the van der Waals radius, meaning 0.7, 0.8 or 1.0. At a factor of 1.0 you will have the most realistic view, but it is very bulky. At 0.7 the structure becomes more apparent. The print shown was made through selective laser sintering, no supports were required. You will need supports for fused deposition modeling of course. After printing, the two trimer halves could be separated and one halve was stained black. The glucose molecule shown for size comparison can be found here: https://www.thingiverse.com/thing:4791044 The insulin monomer can be found here: https://www.thingiverse.com/thing:4792658 Scale to desired size. Let me know if you need a specific molecule, maybe I can help.

Download Model from thingiverse

With this file you will be able to print Insulin Hexamer with your 3D printer. Click on the button and save the file on your computer to work, edit or customize your design. You can also find more 3D designs for printers on Insulin Hexamer.