HIV-1 Protease

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HIV-1 protease is a powerful enzyme that drives the rapid growth of retroviruses and oversees the complex process of gag and gag-pol during virion maturation. Its dimeric structure provides crucial docking sites for essential ligands, including primary inhibitors and active centers that orchestrate the molecule's function to develop effective anti-AIDS medications that can slow down the progression of the HIV virus. In this illustration, HIV-1 protease displays key characteristics of the protein, highlighting its interaction with a critical inhibitor that has enabled the development of a groundbreaking drug called saquinavir to combat HIV/AIDS.