Eosinophilic leukocyte blood cell model Low-poly 3D model

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Eosinophilic granulocytes, commonly known as eosinophils or acidophils, are immune cells that combat multicellular parasites and certain infections in vertebrates, while also regulating allergy and asthma mechanisms alongside mast cells. Developing in the bone marrow, they enter peripheral blood post-hematopoiesis. These eosinophilic cells are transparent but turn brick-red when stained with eosin, a red, acidic dye. Their cytoplasm contains granules packed with chemical mediators like histamine and proteins such as eosinophil peroxidase, ribonucleases, deoxyribonucleases, lipase, plasminogen, and major basic protein. Upon activation, these mediators are released through degranulation, exhibiting toxicity to parasite and host tissues. Typically, eosinophils constitute 1-6% of white blood cells and measure 12-17 micrometers in size. In normal conditions, they're found in bone marrow, gastrointestinal tract, ovary, uterus, spleen, and lymph nodes but are absent from organs like lung, skin, and esophagus unless associated with diseases. Eosinophils circulate for 8-12 hours and can survive in tissues for an additional 8-12 days sans stimulation.