DNA repair enzyme MutS from E. coli

thingiverse

The DNA-copying machinery makes approximately one error per 10 million bases. While this may be acceptable for bacterium with only 5 million bases, a replication rate of once per hour means that half of the progeny will have mutations on average. This percentage increases rapidly, nearing 100% by the end of the day. Consequently, E. coli requires additional mechanisms to prevent DNA mutation aside from proofreading polymerases. MutS protein is one such mechanism; it binds to mismatched base pairs and enlists other proteins for repair. For more information, visit http://en.wikipedia.org/wiki/MutS-1. Meanwhile, the model was obtained from PDB structure 3zlj and printed using KISSlicer with a layer height of 0.15, an extrusion width of 0.5mm, 15% infill, and a support flow rate reduced to 75% by an external script.