COAGULATION CASCADE COMMON PATHWAY
sketchfab
A realistic model portrays a segment of blood clot formation. Made from procedural materials, it doesn't rely on UV maps or image textures. The coagulation cascade is typically divided into intrinsic and extrinsic pathways, both of which merge at the point where factor X is activated, launching the common pathway. A vascular injury exposes tissue factor, which binds with factor VIIa and calcium to prompt the conversion of factor X to Xa. Activated factor X (Xa) combines with its cofactor (factor V), tissue phospholipids, platelet phospholipids, and calcium to form the prothrombinase complex, which converts prothrombin (II) into thrombin (IIa).
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