Carbonic Anhydrase II

Carbonic Anhydrase II

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Human carbonic anhydrase II is intricately bound with acetazolamide. The three-dimensional structure of this binding was obtained from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (PDB), specifically entry 3HS4. This work originated in the groundbreaking study "High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design" by Sippel, K.H., Robbins, A.H., Domsic, J., Genis, C., Agbandje-McKenna, M., and McKenna, R. (2009), published in Acta Crystallographica Section F, Volume 65, Pages 992-995.

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