Aspirin bound to Cycloxygenase-2 (COX-2)

Aspirin bound to Cycloxygenase-2 (COX-2)

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The Molecular Foundation of Aspirin Function Uncovered through the Crystal Structure of Inactive Prostaglandin H2 Synthase DOI: 10.2210/pdb1PTH/pdb **Note: The Bromine atom of the brominated acetyl group in the X-Ray structure was removed for educational purposes. The molecular foundation of aspirin function uncovered through the crystal structure of inactive prostaglandin H2 synthase. Loll, P.J., Picot, D., Garavito, R.M. (1995) Nat.Struct.Mol.Biol. 2: 637-643

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