
Apoferritin (from P.furiosus) protein structure
prusaprinters
<p>This is a model of the apoferritin protein from <i>Pyrococcus furiosus</i> at a scale of 1 to 1,000,000 and at roughly 6 Angstrom resolution. One millimeter in the printed model is therefore roughly the size of a hydrogen atom. A very similar, human version of this protein is responsible for transporting iron around our bodies.</p><p>Ferritin exhibits octahedral symmetry. It consists of 24 asymmetric units. The model has to be printed 24 times. Two units are glued together to form a dimer, and 12 of these dimers can be assembled using the sticks and holes in the model.</p><p>Assembly can be tricky. (Tip: Assemble three dimers around the 3-fold axis first. Do this four times and then assemble everything)</p><p>Printing is possible with single perimeter, no infill, no top and bottom layers. Modifier slab for the first millimeter of the print with 10 perimeters will help with first-layer adhesion and stability. Modifier with 2 perimeters for the sticks make them more stable.</p><p>The model is based on this 3D density: <a href="https://www.ebi.ac.uk/emdb/EMD-12901">https://www.ebi.ac.uk/emdb/EMD-12901</a> and this atomic model <a href="https://www.ebi.ac.uk/pdbe/entry/pdb/7ohf">https://www.ebi.ac.uk/pdbe/entry/pdb/7ohf</a></p><p> </p><p> </p>
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