16-base-pair B-DNA Molecular Structure

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The intricate molecular structure of a 16-base-pair B-DNA model was meticulously crafted using the powerful visualization tool Jmol, which expertly interprets X-ray diffraction crystal structure data sourced from the Protein Data Bank (PDB ID 3BSE). A direct link to this pivotal dataset can be found at http://jmol.sourceforge.net/, and its Digital Object Identifier is 10.2210/pdb3BSE/pdb. Researchers Narayana, N. and Weiss, M. conducted a comprehensive crystallographic analysis of a sex-specific enhancer element in their groundbreaking study published in the Journal of Molecular Biology (2009). This pioneering research delves into the complex sequence-dependent DNA structure, hydration patterns, and dynamic properties, shedding new light on the fundamental mechanisms governing gene expression. The study's findings are documented under PMID: 18992257 and DOI: 10.1016/j.jmb.2008.10.041.